A review of pain experienced during topical photodynamic therapy--our experience in Dundee.

Review of photodynamic therapy in actinic keratosis and basal cell carcinoma

The number of non-melanoma skin cancers is increasing worldwide, and so also the demand for effective treatment modalities. Topical photodynamic therapy (PDT) using aminolaevulinic acid or its methyl ester has recently become good treatment options for actinic keratosis and basal cell carcinoma; especielly when treating large areas and areas with field cancerization. The cure rates are usually ...

Immediate whealing urticaria in red light exposed areas during photodynamic therapy.

One of the recommended first-line treatments for basal cell carcinomas, actinic keratoses and Bowen's disease is photodynamic therapy. Commonly associated side- effects include pain and phototoxicity. Histamine release is a part of this reaction, but whealing urticaria follow noting photodynamic therapy has only been reported by the manufacturer. The aim of this study was to investigate the pre...

Morphine gel 0.3% does not relieve pain during topical photodynamic therapy: a randomized, double-blind, placebo-controlled study.

There is a demand for pain relief during photodynamic therapy. We therefore investigated the efficacy and side-effects of topical morphine gel 0.3% for pain relief during topical photodynamic therapy in a randomized, double-blind, placebo-controlled study. The study involved 28 patients with actinic keratoses or basal cell carcinomas. Each patient was treated with photodynamic therapy after sup...

Is Photodynamic Therapy Effective in Treatment of Periodontal Diseases? A Review of Literature

A Review on Experimental Assessments of Pain Threshold in Healthy Human Subjects

A B S T R A C T There are three types of nerve fibers that are involved in the transmission of pain stimuli: C fibers (slower fibers) for thermal, mechanical and chemical stimuli, A-delta fibers for thermal or mechanical stimuli and A-beta fibers for touch stimuli. Clinically, this is crucial in making an accurate assessment of the pain level experienced by a suffering patient, in indicating th...